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First Pass Shunt Analysis

Hermes Hybrid Viewer™ NM Processing First Pass Shunt Analysis

HERMES FUGA (FUnctional Gated Analysis) program is used to analyze data from planar gated blood pool studies of the heart.

• Automatic edge detection
• Amplitude and phase images
• Left & right ventricular analysis
• Movie display

The FUGA (FUnctional Gated Analysis) program is used to analyze data from planar gated blood pool studies of the heart.
HERMES FUGA™ uses cycle-dependent background correction to correct the counts within the end diastolic region for non-ventricular counts.

The counts within the end diastolic region, corrected for cycle-dependent background, are used for the calculation of ejection fraction, regional ejection fraction (6),
filling and emptying rates (5) and the final volume curve. This method has been shown (1)to minimize inter-operator variability when generating time-activity
curves and is therefore ideally suited for calculating ventricular function parameters. The left ventricular edge detection is performed automatically using a
variation on a second derivative method developed at Yale University (1).


Summery of features

• Automatic edge detection using filtered data and amplitude/phase images, manually adjustable
• Automatic but adjustable background region
• Calculation of several global and regional parameters
• Movie of phase image and phase histogram, wall motion and volume-flow curve

Quantitative Results

• Global ejection fraction of right or left ventricle
• Regional ejection fraction in relative or absolute mode
• Regional wall motion
• Peak filling/emptying rate
• Time to peak filling/emptying rate
• Filling fraction


1. Forrester AL, Fetterman R, Zaret BL, Wackers F.J.Th. Rapid radionuclide-derived systolic and diastolic cardiac function using cycle-dependent background correction and Fourier analysis. Proc Computers in Cardiology1985; Linkoping, Sweden
2. Sorensen SG, Hamilton GW, Williams DL, Richie JL. R-wave synchronized blood-pool imaging. A comparison of the accuracy and reproducibility of fixed and computer automated varying regions of interest for determining the left ventricular ejection fraction. Radiology1979; 131:437-8
3. Pavel D, Byrom E, Lam W, et al. Detection and quantification of regional wall motion abnormalities using phase analysis of equilibrium gated cardiac studies. Clinical Nuclear Medicine1983; 8(7):315-321
4. Poliner LR; Farber SH; Glaeser DH; Nylaan L; Verani MS; Roberts R. Alteration of diastolic filling rate during exercise radionuclide angiography: a highly sensitive technique for detection of coronary artery disease. Circulation1984;70(6):942-50
5. Miller TD et al. Quantitative measures of regional asynergy add independent prognostic information to left ventricular ejection fraction in patients with prior myocardial infarction. Am Heart J. 1997;133(6):640-7

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